Effect of experimental hyperthyroidism on skeletal-muscle proteolysis

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Effect of experimental hyperthyroidism on skeletal-muscle proteolysis.

It is not clear whether the muscle wasting commonly observed in hyperthyroidism is due to alteration in the rate of protein synthesis or degradation. The effect of experimental hyperthyroidism on skeletal-muscle proteolysis in the rat was studied by measuring alanine and tyrosine release from isolated skeletal muscles in vitro and 3-methyl-histidine excretion in vivo. Alanine release from the i...

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ژورنال

عنوان ژورنال: Biochemical Journal

سال: 1981

ISSN: 0264-6021

DOI: 10.1042/bj1940685